Product Description

NOVANTRONE INJECTION (Mitoxantrone HCl) is a potent chemotherapeutic agent used primarily for the treatment of certain types of cancer, including prostate cancer and multiple sclerosis. Each vial contains 2 mg/ml of Mitoxantrone, providing a total of 10 ml of solution for injection.

Indications

NOVANTRONE is indicated for the treatment of patients with advanced hormone-refractory prostate cancer and for the management of secondary progressive multiple sclerosis. It may also be used in other conditions as determined by a healthcare provider.

Mechanism of Action

Mitoxantrone works by interfering with the DNA replication process in cancer cells, ultimately inhibiting their growth and proliferation. Its anthracenedione structure allows it to intercalate into DNA, leading to cell cycle arrest and apoptosis.

Administration

NOVANTRONE is administered intravenously under the supervision of a qualified healthcare professional. Dosage and frequency of administration will be determined based on the specific condition being treated and patient response.

Side Effects

Common side effects may include nausea, vomiting, hair loss, and fatigue. Patients should be monitored for potential adverse effects, including cardiotoxicity and myelosuppression, which may require dose adjustments or discontinuation of therapy.

Precautions

Prior to treatment, patients should inform their healthcare provider of any existing medical conditions, allergies, or medications they are taking. Regular monitoring of blood counts and cardiac function is recommended during treatment with NOVANTRONE.

Storage

Store NOVANTRONE at room temperature, away from direct light and moisture. Keep out of reach of children.

Consultation

For more information on NOVANTRONE INJECTION, consult your healthcare provider or pharmacist. It is essential to discuss any concerns or questions regarding treatment and potential side effects.