Duphaston is a prescription medication containing Dydrogesterone, a synthetic form of the female hormone progesterone. It is used to treat a variety of menstrual and reproductive health issues, including irregular periods, painful menstruation, endometriosis, infertility due to luteal phase insufficiency, and to prevent miscarriage in cases of recurrent pregnancy loss. Duphaston helps restore hormonal balance, supporting a healthy menstrual cycle and pregnancy.

Drug Class:

• Drug Class: Progestogen, Hormonal Therapy
• Categories: Menstrual Health, Infertility Treatment, Pregnancy Support

Active Ingredient Name:

• Active Ingredient: Dydrogesterone

Popular and Other Names:

• Brand Name: Duphaston
• Generic Name: Dydrogesterone
• Other Names: Synthetic Progesterone Tablets, Duphastan

Mode of Action:

Duphaston works by mimicking the natural hormone progesterone, which plays a crucial role in regulating the menstrual cycle and maintaining pregnancy:

1. Restores Hormonal Balance: Dydrogesterone in Duphaston compensates for low progesterone levels, regulating the menstrual cycle and preventing menstrual disorders like irregular periods, painful periods, and heavy bleeding.

2. Supports Pregnancy: In women experiencing luteal phase insufficiency or recurrent miscarriage, Duphaston helps maintain the lining of the uterus, promoting a healthy environment for embryo implantation and pregnancy maintenance.

3. Manages Endometriosis: Duphaston reduces the growth of endometrial tissue in women with endometriosis, alleviating pain and discomfort associated with the condition.

How to Use It:

Duphaston is taken orally, usually under the supervision of a healthcare provider. The dosage and duration of treatment vary depending on the condition being treated.

Recommended Dosage:

• Irregular Menstrual Cycle: 1 tablet (10 mg) twice daily from day 11 to day 25 of the cycle.
• Endometriosis: 1-3 tablets (10 mg) daily from day 5 to day 25 of the cycle or continuously.
• Infertility: 1 tablet daily from day 14 to day 25 of the cycle for at least 6 consecutive cycles or as directed.
• Miscarriage Prevention: 1 tablet twice daily until the 20th week of pregnancy, as prescribed by a healthcare provider.

Directions:

1. Take with Water: Swallow the tablet whole with a full glass of water.
2. Follow Schedule: Stick to the schedule recommended by your healthcare provider, especially if using Duphaston for infertility or pregnancy support.

Cautions:

• Pregnancy and Breastfeeding: Duphaston is safe to use during pregnancy for miscarriage prevention. However, consult your healthcare provider if you are breastfeeding.
• Liver Disease: Use with caution in patients with liver disorders.
• Allergic Reactions: Avoid using Duphaston if you are allergic to dydrogesterone or any other component of the tablet.

Managing Side Effects:

• Common Side Effects: Headache, nausea, dizziness, and bloating.
• Serious Side Effects: Severe allergic reactions (e.g., rash, swelling), jaundice, or abnormal vaginal bleeding. If these occur, discontinue use and seek medical attention.
• Management Tips: To minimize side effects, take Duphaston with meals. If symptoms persist or worsen, consult a healthcare provider.

Guidelines:

1. Adherence to Treatment: For best results, take Duphaston as prescribed. Do not discontinue treatment abruptly, especially if using it for pregnancy support.
2. Regular Monitoring: If taking Duphaston for long-term conditions like endometriosis, regular follow-ups with your healthcare provider are essential.
3. Consult Before Use: Always consult a healthcare provider before starting Duphaston, especially if you have existing health conditions or are taking other medications.

Frequently Asked Questions (FAQs)

1. What is Duphaston used for?

   • Duphaston is used to treat menstrual disorders, infertility due to luteal phase insufficiency, endometriosis, and to prevent miscarriage in early pregnancy.

2. How does Duphaston work in pregnancy?

   • Duphaston supports pregnancy by mimicking progesterone, which is necessary for maintaining the uterine lining and preventing miscarriage, especially in cases of luteal phase defects.

3. Can I use Duphaston for irregular periods?

   • Yes, Duphaston is commonly used to regulate irregular menstrual cycles by compensating for low progesterone levels.

4. Is Duphaston safe during pregnancy?

   • Duphaston is safe to use during pregnancy, especially to prevent miscarriage. However, always follow your healthcare provider’s advice.

5. What should I do if I miss a dose of Duphaston?

   • If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip the missed dose and continue your regular schedule. Do not double the dose.

6. How long should I take Duphaston?

   • The duration of Duphaston treatment depends on your condition and response to treatment. Always follow your healthcare provider’s recommendations.

7. Can I stop taking Duphaston abruptly?

   • No, you should not stop taking Duphaston suddenly, especially if taking it for pregnancy support, as this may lead to complications. Consult your doctor for advice.