Edaravone
Edaravone is a medication used to treat amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ALS is a progressive neurodegenerative disorder that affects nerve cells in the brain and spinal cord. Edaravone works as a free radical scavenger, which helps reduce oxidative stress—a factor believed to contribute to the nerve damage seen in ALS patients. It may slow the progression of the disease and improve daily functioning.
Standard Dosage: Edaravone is administered intravenously. The typical regimen involves a 60 mg dose given as an infusion over 60 minutes.
Initial treatment cycle: Daily infusions for 14 consecutive days, followed by a 14-day drug-free period.
Subsequent cycles: Daily infusions for 10 out of 14 days, followed by a 14-day drug-free period.
Edaravone should be administered by a healthcare professional.
The infusion should be given over 60 minutes through an intravenous line.
Follow the prescribed dosing schedule precisely, including drug-free periods.
Ensure that the infusion site is monitored for any signs of adverse reactions during and after administration.
Inform your healthcare provider of any allergies or medical conditions, especially asthma or sulfite sensitivity, as Edaravone contains sodium bisulfite.
Notify your healthcare provider of all medications you are currently taking to avoid potential drug interactions.
Edaravone can cause allergic reactions; immediate medical attention is required if you experience symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing.
Pregnant or breastfeeding women should consult their healthcare provider before using this medication.
Guidelines:
Regularly monitor for any side effects and report them to your healthcare provider.
Maintain good hydration and follow a balanced diet to support overall health during treatment.
Store Edaravone in the original packaging until ready for use, and follow storage instructions provided by the healthcare professional.
Report any severe or persistent side effects to your healthcare provider immediately.
Q: What should I do if I miss a dose?
A: If you miss a scheduled infusion, contact your healthcare provider immediately to discuss the best course of action.
Q: Can Edaravone cure ALS?
A: Edaravone is not a cure for ALS but may help slow the progression of the disease and improve daily functioning.
Q: Are there any common side effects?
A: Common side effects include bruising, gait disturbances, headache, and fatigue. Contact your healthcare provider if these effects persist or worsen.
Q: Can I take other medications while using Edaravone?
A: Some medications can interact with Edaravone, potentially decreasing its effectiveness or increasing side effects. Always inform your healthcare provider about all the medications and supplements you are taking.
Q: Is Edaravone safe during pregnancy?
A: The safety of Edaravone during pregnancy is not well established. If you are pregnant or planning to become pregnant, consult your healthcare provider to weigh the potential benefits and risks.
Q: How should I store Edaravone?
A: Store Edaravone in the original packaging at the recommended temperature until ready for use. Keep it out of reach of children.
Q: Can I drive while taking Edaravone?
A: Edaravone can cause dizziness and fatigue. Use caution when driving or operating machinery until you know how the medication affects you.
Q: How long do I need to take Edaravone?
A: The duration of treatment with Edaravone depends on your specific condition and response to the medication. Follow your healthcare provider’s instructions regarding the length of treatment.
Q: What if I experience severe side effects?
A: If you experience severe side effects such as allergic reactions or significant changes in health, seek medical attention immediately.
By following these guidelines and using Edaravone as prescribed, you can effectively manage your ALS treatment and maintain your health. Always consult your healthcare provider for personalized advice and information.
Prescription Required 
India
