We do not dispense any prescription medicine without vaild and legible prescription writen by your local physician. All prescription must be presented from a valid verifiable and licensed physician.
We are only able to ship a maximum 90-day supply of your prescription.
All trademarks and registered trademark are the property of there respective owners. The product mentioned on this website are trademarks of their respective owners and are not owned by or affiliated with waldrugmart.com or any of its associated company.
About Product
Sofosbuvir and Velpatasvir (Epclusa) Product Description
Sofosbuvir and Velpatasvir (Epclusa) 400/100mg 28 Tablets
Sofosbuvir and Velpatasvir, marketed under the brand name Epclusa, is a prescription medication designed for the treatment of chronic hepatitis C virus (HCV) infections. This combination therapy is effective against all major genotypes of the virus, offering a comprehensive solution for patients seeking to eradicate HCV from their system.
Sofosbuvir and Velpatasvir Combination Tablets - Medicine Description
Sofosbuvir and Velpatasvir Combination Tablets are used in the treatment of chronic Hepatitis C virus (HCV) infection in adults. Marketed under the brand name Epclusa, this combination drug provides a comprehensive treatment option for all genotypes of the Hepatitis C virus, making it a versatile choice for patients with or without cirrhosis. The combination includes Sofosbuvir and Velpatasvir, two potent direct-acting antivirals that work together to stop the virus from replicating and promote viral clearance from the body.
Drug Class:
Drug Class: Direct-acting Antivirals (DAA)
Categories: Antiviral Agent, Hepatitis C Treatment
Active Ingredient Name:
Active Ingredients: Sofosbuvir (400 mg) and Velpatasvir (100 mg)
Popular and Other Names:
Brand Name: Epclusa
Generic Name: Sofosbuvir and Velpatasvir
Other Names: Sofosbuvir-Velpatasvir Tablets
Mode of Action:
The combination of Sofosbuvir and Velpatasvir works synergistically to inhibit the replication of the Hepatitis C virus:
Sofosbuvir is a nucleotide analog inhibitor of the NS5B RNA-dependent RNA polymerase enzyme, which is critical for viral RNA replication.
Velpatasvir is an NS5A inhibitor that disrupts the assembly and replication of the virus. Together, they block the viral lifecycle at multiple stages, preventing the virus from multiplying and reducing the viral load in the body.
How to Use It:
Sofosbuvir and Velpatasvir combination tablets are taken orally, once daily, with or without food. The tablets should be swallowed whole without chewing, crushing, or breaking them.
Recommended Dosage:
Standard Dosage: One tablet (Sofosbuvir 400 mg + Velpatasvir 100 mg) once daily for 12 weeks.
Special Considerations: For patients with decompensated cirrhosis, the combination is usually administered with ribavirin for 12 weeks. Dosage adjustments are based on patient condition and treatment response.
Directions:
Take the medication at the same time each day to maintain consistent levels in the blood.
Do not skip doses or discontinue use without consulting your healthcare provider, as this may lead to drug resistance or treatment failure.
If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose and resume your regular schedule.
Cautions:
Pregnancy and Breastfeeding: Not recommended for use during pregnancy, particularly if combined with ribavirin. Women of childbearing age should use effective contraception during and after treatment.
Drug Interactions: Sofosbuvir and Velpatasvir can interact with other medications, such as antacids, St. John’s Wort, rifampin, and certain anticonvulsants. Always inform your healthcare provider about all medications and supplements you are taking.
Liver Function: Regular liver function tests are recommended to monitor the effectiveness of the treatment.
Do Not Use With Amiodarone: The combination can cause life-threatening bradycardia when used with amiodarone.
Managing Side Effects:
Common Side Effects: Headache, fatigue, nausea, and insomnia.
Serious Side Effects: Symptoms of liver problems (yellowing of the skin or eyes, dark urine), chest pain, or shortness of breath. Seek immediate medical attention if these symptoms occur.
Management Tips: For mild side effects, drink plenty of water, get adequate rest, and take medications like acetaminophen (as advised by your healthcare provider). If side effects persist, consult your doctor.
Guidelines:
Continue taking Sofosbuvir and Velpatasvir for the full duration of the treatment course, even if you start feeling better.
Avoid alcohol, as it can increase the risk of liver damage.
Regular blood tests are necessary to monitor liver function and treatment efficacy.
Do not take this medication along with other drugs for Hepatitis C unless directed by a healthcare provider.
Frequently Asked Questions (FAQs)
What is Sofosbuvir and Velpatasvir used for?
This combination is used for the treatment of chronic Hepatitis C infection across all genotypes (genotypes 1 to 6). It is effective for patients both with and without cirrhosis.
Can Sofosbuvir and Velpatasvir cure Hepatitis C?
Yes, when taken as directed, this combination can achieve a sustained virologic response (SVR), which is considered a "functional cure" for Hepatitis C.
What are the common side effects of Sofosbuvir and Velpatasvir?
The most common side effects include headache, fatigue, and nausea. These symptoms are usually mild and improve over time.
Is it safe to use Sofosbuvir and Velpatasvir during pregnancy?
It is not recommended during pregnancy, especially when used with ribavirin. Women should use effective contraception during and for 6 months after treatment.
Can I drink alcohol while taking Sofosbuvir and Velpatasvir?
Avoid alcohol during treatment, as it can increase the risk of liver damage and affect treatment outcomes.
How long is the treatment duration?
The standard treatment duration is 12 weeks, but this may vary depending on the presence of cirrhosis or other health conditions.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember, but do not double the next dose to make up for the missed one.
Can I take antacids with Sofosbuvir and Velpatasvir?
Avoid taking antacids within 4 hours of taking Sofosbuvir and Velpatasvir, as they can reduce the absorption and effectiveness of the medication.
What types of medications and health products are available?
Our product pages feature a comprehensive range of FDA-approved prescription medications, affordable generic drugs, and over-the-counter (OTC) health products. Whether you’re looking for treatments for chronic conditions, acute care solutions, or wellness supplements, you’ll find both brand-name and generic options tailored to your needs.
Are the products listed on our website FDA-approved and safe?
Absolutely. Every medication on our product pages is FDA-approved and sourced from licensed, reputable pharmacies. We adhere to strict quality control protocols to ensure that both our brand-name and generic drugs meet the highest safety and efficacy standards.
How do I verify product details and usage instructions?
Each product page includes detailed information such as dosage instructions, benefits, and potential side effects. Our licensed pharmacists review and update these details regularly to ensure accuracy. For brand-name products, you’ll find information about the manufacturer’s guidelines, while generic listings include bioequivalence data demonstrating they offer the same therapeutic effects.
What are the differences between brand-name and generic medications?
Brand-name drugs are developed by pharmaceutical companies and marketed under a proprietary name, often featuring extensive research and clinical trials. Generic medications, on the other hand, contain the same active ingredients, dosage, safety, and efficacy as their brand-name counterparts but are typically offered at a lower cost. Both options are FDA-approved, ensuring you receive safe and effective treatment regardless of your choice.
Can I compare prices and find discounts on medications?
Yes! Our product pages offer transparent pricing with no hidden fees. Use our built-in price comparison tool to find the best deals on both generic and brand-name drugs. We also offer pharmacy discount cards, seasonal promotions, and loyalty rewards to help you save even more on your medications.
What shipping options are available for orders placed through your product pages?
We provide multiple shipping options—from standard to expedited shipping—to meet your needs. All orders are discreetly packaged and shipped securely, whether you’re ordering locally or internationally. Delivery times and restrictions vary by destination, so please review our shipping policy or contact our support team for details.
How does the auto-refill feature work for recurring medications?
Our product pages let you easily set up auto-refill reminders for your prescriptions. Once enrolled, you can schedule regular refills through your account dashboard, ensuring you never run out of essential medications while saving valuable time.
Is my personal and payment information secure when ordering?
Yes. We use industry-standard encryption and HIPAA-compliant systems to safeguard your personal, medical, and payment information. All transactions on our product pages are processed securely, so you can shop with complete peace of mind.
What should I do if a product is out of stock or unavailable?
We work closely with trusted suppliers to minimize delays. If a medication is out of stock, our system will notify you immediately and suggest available alternatives or provide expedited restock updates. Our customer support team is always available to assist with any inquiries.
How do I contact customer support for questions about a product?
Our dedicated customer support team is available 24/7 via live chat, phone, or email. Whether you have questions about product details, pricing, shipping, or need help comparing brand-name and generic options, we’re here to ensure you receive personalized assistance.
Do you offer guidance on choosing the right medication for me?
Yes. Our licensed pharmacists are available for online consultations and can offer personalized recommendations based on your healthcare needs. Visit our telehealth section to connect with a professional and receive guidance on selecting the best treatment—whether you’re considering a brand-name drug or its generic equivalent.
Resof Total (Sofosbuvir & Velpatasvir) 400/100mg 28 Tablets
Generic Product
USD $468.00
Active Ingredient: Sofosbuvir and Velpatasvir
This website uses cookies to improve your experience. By clicking “Accept”, you consent to the use of ALL the cookies. However you may visit Cookie Settings to provide a controlled consent.