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Products matching the full generic name: Regorafenib
IndiaStivarga (Regorafenib) is a medication used to treat certain types of cancer. It functions as a kinase inhibitor, which helps slow down the growth and spread of cancer cells in the body. Stivarga is specifically approved for use in the treatment of metastatic colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (HCC) that have progressed after prior treatments.
Stivarga works by blocking multiple enzymes that promote cancer growth. It targets several kinases involved in tumor growth and angiogenesis, which is the formation of new blood vessels that supply the tumor. By inhibiting these kinases, Stivarga helps to reduce tumor growth and spread.
Patients diagnosed with metastatic colorectal cancer, gastrointestinal stromal tumors, or hepatocellular carcinoma that have not responded to previous treatments may benefit from Stivarga. It is important for patients to discuss with their healthcare provider to determine if Stivarga is an appropriate option for their specific condition.
The recommended dose of Stivarga is 160 mg taken orally once daily for 21 days, followed by 7 days off therapy. This cycle is repeated every 28 days. It is crucial to follow the healthcare provider's instructions and not to alter the dosage without consulting them.
Common side effects of Stivarga may include fatigue, loss of appetite, hand-foot skin reaction, diarrhea, and weight loss. More serious side effects can occur and should be reported to a healthcare provider immediately. These may include severe liver problems, bleeding, high blood pressure, heart problems, and severe skin reactions.
Before starting Stivarga, inform the healthcare provider of any existing medical conditions, including liver problems, high blood pressure, bleeding problems, heart problems, or recent surgeries. Regular monitoring through blood tests and other assessments may be necessary to check for side effects and adjust treatment as needed.
Stivarga should be stored at room temperature, away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children and pets. Do not use beyond the expiration date indicated on the packaging.
Stivarga may interact with other medications, which could affect how it works or increase the risk of side effects. It is important to inform the healthcare provider about all medications, supplements, and herbal products currently being taken. The healthcare provider can help manage any potential interactions.
If a dose of Stivarga is missed, it should be taken as soon as remembered on the same day. If it is already the next day, skip the missed dose and continue with the regular dosing schedule. Do not take double doses to make up for a missed one.
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