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Products matching the full generic name: Regorafenib
Stivarge or Nublexa, known by its generic name Regorafenib, is a medication used in the treatment of certain types of cancer. It is classified as a multi-kinase inhibitor, which works by blocking specific proteins that promote cancer cell growth, thereby helping to slow down the progression of the disease.
Regorafenib functions by targeting multiple protein kinases involved in tumor angiogenesis, oncogenesis, and the tumor microenvironment. By inhibiting these kinases, Regorafenib helps reduce blood supply to the tumor, inhibiting its growth and spread.
Stivarge or Nublexa is primarily prescribed for the treatment of metastatic colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (HCC) in patients who have been previously treated with other therapies but have not responded.
Regorafenib is administered orally in the form of tablets. It is typically taken once daily for three weeks, followed by a one-week break, making up a 28-day cycle. It is important to follow the prescribing doctor's instructions and to take the medication with a low-fat breakfast to enhance absorption.
Common side effects of Regorafenib may include fatigue, decreased appetite, hand-foot skin reactions, diarrhea, and hypertension. Patients should report any severe or persistent side effects to their healthcare provider promptly.
Patients with known hypersensitivity to Regorafenib or any of its components should not take this medication. It is also not recommended for use in pregnant or breastfeeding women due to potential risks to the fetus or infant.
Before starting Regorafenib, inform your healthcare provider about any other medical conditions, especially liver problems, bleeding disorders, or heart conditions. Regular monitoring of liver function and blood pressure is recommended during treatment.
Yes, Regorafenib can interact with other medications, which may affect how it works or increase the risk of side effects. Inform your doctor about all medications and supplements you are taking to avoid potential interactions.
For more detailed information, consult the product's prescribing information or speak with a healthcare professional. They can provide guidance tailored to your specific health needs and circumstances.
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