Udiliv - Comprehensive Medicine Description

Udiliv is a prescription medication primarily used to treat various liver conditions, such as chronic liver disease, gallstones, and primary biliary cirrhosis. It contains Ursodeoxycholic Acid (UDCA), which helps improve liver function by reducing bile acid toxicity and promoting bile flow. Udiliv is often prescribed to alleviate symptoms associated with liver dysfunction and to prevent the formation of cholesterol gallstones.

Drug Class:

• Drug Class: Hepatoprotective Agent
• Categories: Cholagogue, Choleretic, Bile Acid Therapy

Active Ingredient Name:

• Active Ingredient: Ursodeoxycholic Acid (UDCA)

Popular and Other Names:

• Brand Names: Udiliv, Urso, Ursocol, Ursodiol
• Generic Name: Ursodeoxycholic Acid (UDCA)
• Other Names: Ursodiol, Ursodex, Udihep

Mode of Action:

Ursodeoxycholic Acid (UDCA), the active ingredient in Udiliv, works by altering the composition of bile. It decreases the cholesterol content in bile by suppressing the liver’s synthesis and secretion of cholesterol. This action helps dissolve cholesterol-based gallstones. Additionally, UDCA has a hepatoprotective effect by reducing the toxic load of bile acids on liver cells, thereby decreasing inflammation and fibrosis in conditions like primary biliary cirrhosis. It also enhances bile flow, promoting better liver function and relieving symptoms such as jaundice and itching.

How to Use It:

Udiliv is available in tablet form and should be taken as directed by a healthcare professional. The dosage and duration depend on the condition being treated and the patient’s response to therapy.

Recommended Dosage:

• Chronic Liver Diseases & Primary Biliary Cirrhosis:
  • Standard Dose: 13-15 mg/kg/day in divided doses.
  • For Severe Cases: The dose may be increased based on the physician’s recommendations.
• Gallstone Dissolution:
  • Dosage: 8-10 mg/kg/day, taken in 2 or 3 divided doses.
  • Duration: Typically continued for 6-12 months or as advised by a healthcare provider.

Always consult your healthcare provider for the appropriate dosage tailored to your condition.

Directions:

• Take the tablets orally, with or without food, at the same time every day.
• Swallow the tablet whole with water; do not crush or chew it.
• Follow your doctor’s directions regarding dosage frequency and duration.
• If prescribed multiple doses per day, space them evenly throughout the day.

Cautions:

• Allergy: Do not use Udiliv if you are allergic to Ursodeoxycholic Acid or any of its components.
• Severe Liver Conditions: Use with caution in patients with severe liver dysfunction or cirrhosis, as it may worsen the condition.
• Gallbladder Function: Avoid in patients with non-functional gallbladders.
• Pregnancy and Breastfeeding: Udiliv should be used during pregnancy or breastfeeding only if clearly needed and prescribed by a healthcare professional.
• Drug Interactions: Antacids containing aluminum, certain lipid-lowering agents, and estrogen therapy can reduce the effectiveness of Udiliv. Inform your doctor about all medications and supplements you are taking.

Manage Side Effects:

• Common Side Effects: Nausea, diarrhea, abdominal pain, dizziness, and rash.
• Severe Side Effects: Yellowing of the skin or eyes (jaundice), severe abdominal pain, or signs of an allergic reaction (rash, itching, swelling).
• Management Tips: For mild symptoms such as nausea or diarrhea, take Udiliv with food and stay hydrated. If severe symptoms occur, discontinue use and seek immediate medical attention.

Guidelines:

• Regular Monitoring: Regular liver function tests (LFTs) are recommended to monitor the effectiveness of Udiliv and detect any potential adverse effects.
• Avoid Fatty Foods: To maximize the effectiveness of the treatment, avoid high-fat and cholesterol-rich foods.
• Adherence to Treatment: For gallstone treatment, adhere strictly to the prescribed regimen, as discontinuation may lead to gallstone recurrence.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose. Do not double the dose.

Frequently Asked Questions (FAQs):

1. What is Udiliv used for?

   • Udiliv is used for the treatment of chronic liver diseases, gallstone dissolution, and primary biliary cirrhosis. It improves liver function and prevents gallstone formation.

2. How does Udiliv work?

   • Udiliv works by reducing bile acid toxicity, promoting bile flow, and decreasing cholesterol levels in bile, which helps dissolve cholesterol gallstones and protects liver cells.

3. Can Udiliv dissolve all types of gallstones?

   • No, Udiliv is only effective in dissolving cholesterol-based gallstones. It is not suitable for pigment stones or calcified gallstones.

4. How long does it take for Udiliv to work?

   • Treatment duration depends on the condition being treated. For gallstone dissolution, it may take 6-12 months for complete resolution. Improvement in liver function may take several weeks to months.

5. What are the common side effects of Udiliv?

   • Common side effects include nausea, diarrhea, abdominal pain, and rash. These are usually mild and transient.

6. Can Udiliv be taken during pregnancy?

   • Udiliv should only be used during pregnancy if clearly necessary. Always consult your healthcare provider before starting treatment if you are pregnant or planning to become pregnant.

7. Is Udiliv safe for long-term use?

   • Udiliv is generally safe for long-term use under medical supervision, especially for managing chronic liver conditions like primary biliary cirrhosis.

8. Can Udiliv be used for fatty liver disease?

   • While Udiliv is not specifically indicated for fatty liver disease, it may be prescribed to improve liver function and reduce bile acid toxicity in certain cases.

9. Can I stop taking Udiliv if I feel better?

   • No, you should not discontinue Udiliv without consulting your healthcare provider. Stopping treatment prematurely may lead to recurrence of symptoms or complications.

10. Can Udiliv cause liver toxicity?

    • Udiliv is generally considered hepatoprotective, but in rare cases, it may cause liver toxicity. Regular liver function tests are recommended during treatment.